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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0bd0053954ed2577400a65dbf8372668465e6ef724821b60c69e8ed34642d2f' 
  AND token = 'HVLYYpCXq1h8auENtt9BeSGsuGNaomx+MKfQ6nwn2WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}