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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41f142ce932bd615af1102310289e0d4a4262e5df9a00118180ea9507d7de865' 
  AND token = 'gofhI3ajZZfq8W3SWNqw5wkZDzAn5DMerZ1HFJCMeMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}