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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9d36a770a05c2bcb3e23257d53260adc8468c225718937932df030e4c7a6cd3' 
  AND token = 'GZ1o89I60UgaGtsTyR1QThfqbkMs2JvbYJL7H8sF4wQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}