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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9757eaece551d0c3064221d168a920cfe7c3599b80551d1e7d2bd07412970ab' 
  AND token = 'edyh2GvZyv6DkwMQ/a+y4CQ22J8QI8qO91ymHfEBJyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}