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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d03ccdf14a803ab1a101fccf623958e2d15e66fcf9592fbb826ff5ed02b7fc5' 
  AND token = 'PXDFJSsLw3KPV2TW9JU1nLNfVbfaxC2zns4Pa9wAQKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}