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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35cdc15b1c88e45e7a0e6d8921395d907fe6798dfa32862ce3631f32490f7488' 
  AND token = 'NxbqYjaIEZS/2EINdZiq61mgD9I0kSVGdbpBNPNg5l0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}