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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e591a68589a45a50996a1a65ee387f2924a976544be83300be5c9a8fb2e09ab6' 
  AND token = '+7KpSWgKgIr86QPHlP0VQwNrSc1NSym4svZ0oWdkkVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}