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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4e9ebde72e873ed12c0b11b3e5489eaf2fcc0cafd85f3492ad8fe0de767f4b6' 
  AND token = 'uAumhl7lNRt+DQpJgGeMQSCvD1sfQTEnTe5AVZMYN2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}