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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dc37e3137d8834801ed06b6b318e9c30a7a02b119075bc212c370b7f6a90775' 
  AND token = 'u8TWmwa3Htu9s8HR2KhW+n2rJhnl2gFWVM1sqE3hspU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}