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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3351fdb7419eb2c229edaefde1478d0bc7a263a939f2d8a0f73a0455bf2a3482' 
  AND token = 'Tg7bgjd+EVNMDbUhW8bsACD9p1knf5RY32/hnkqYjwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}