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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e464324e46945a9e3aba100ee4987a9d854769cb9fd3c3bee35bf65c8502202' 
  AND token = 'pf9aWxEZ6kRvk98f6k6cI1k19Qa0MipYdDC2QyLEE8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}