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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '294ef30a7f2f521402a14b859819a12264801692f26049105f4d18a35c568aff' 
  AND token = 'Ta9nbwwoiuaAWLxoPLTMUOh+bo8/v8pz+m3I418w2JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}