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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd117d721c4e3b42202625b6b41e4af0a64d2840b2c028dccc36a249043e87a' 
  AND token = '60HXyz76ANFmTqiOKyF526faQ64AQi1FlfQ1NIe8cmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}