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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21ace98c1b5427bf3c698d9cfd02367318306fd886d87829c331c901733de4b4' 
  AND token = 'z4SmbD8sxW5XMJLAKVuR2NvyNns+jeDzvptPCvJ9KUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}