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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '385022c1005b8177f6e7a5601a8e18df92793c4d52245edd7e6d351db3bb0e3d' 
  AND token = 'bsrMTlD70sN51bE+9uBHTVcC8LBZuj+qZx94LmrKppI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}