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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a72e60299062b628d490aa28d393fe5660162519545333ac5e849c4eaaf6188' 
  AND token = 'WBymxGGVfaRV3FqZnRBY1BD3vqvINm9mtcZEV9iK1FQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}