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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4810287ebb203183b44e43ae5381d26fe08c08450debea02e25698695fd76c33' 
  AND token = 'xqODg2tI52NDI8DtqFXkXsWpWPS2s9I4l9cS2+R3C0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}