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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c26effd2e6a770152e81c53baf5425cb24d8c19cc68fa5c8adccb5de9a49a419' 
  AND token = '0RjyDuQbDP7sRQLEzVc4JQ23dw6BhVJvSYFXCjyr1aE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}