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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed781e129ad1ab7d3b1eb58d7f3b8333c509b0596761cc46c7d2435458d92d76' 
  AND token = 'jhdT9+D0bf52JLuzESzTlAHvXXbNuB567I8egHoUYds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}