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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2729f4f8047a0a346362ce3cb963fd990ddb6eace199129c362cc65a5064759' 
  AND token = '6vBORfwkgKmbUX1NvXPFDdO2iFO2sKd7UdlcaFpwSD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}