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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10801250b096ce20ac8405f673faa4ced250a64008fda4c1194da3e639e3b9a0' 
  AND token = 'v4wSVq2RUEHsW3e6Ii5dsebqctlk/7uujZUmdXd71Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}