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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e02eec9398e96759e465f6da573e7dd34081a57619e4e8a9128b988d24348fa' 
  AND token = 'RmIC+K6vcmzTJxByr5HmW+jLk3It49FdSQBDP6ym8Mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}