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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5085f0423921d96551dad08a1d91e18a6d2680b4d542cdc8fcb918e7e35302c6' 
  AND token = 'VMJLGgws4tvLLMJdNSM2nKHwmNG6nja7T48hrQGJCg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}