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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dce4532a01ff4cc17db5466f79404327bf240bde616fdfdcd80519d1f6f0032a' 
  AND token = 'ONgXprXl9pqyCJ9ZsBGRbqRiHTB1MZuRX4277y4vRPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}