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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f63d2e77d49009e85bf4343385d7ebae0854e4cb800f6a6b6e6df1eaa329039' 
  AND token = 'eD6JiDczM/1VWU+cF0I1xYbUH/PO95s1UJGVDkvEx38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}