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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ca62672bfad3c8c268631aa44b9296ca2246ed28e720f5bdf554de829f391bb' 
  AND token = 'Xxsrzo2QYTtCrgRKi8BHfQhQrzQxXO41yoFF2FzENJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}