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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f01e01f757f4df8e6cce65cd3db34ad70eeff01ac8b38640fd4aab474cf56e7' 
  AND token = 'ILv+/gUdD5nc7rZQQ1bx10scFKNOg6+SPYDvpe3e21w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}