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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '506e7b986444c94eda98c601079e10463ad04574aa0ec1122fac792b2fe2644d' 
  AND token = 'P57W0g1rDXNA+WToocrxiXJnuMTvbBnlUGrO8JhiiN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}