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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca95fc20ec471861e79d4799da58ff732d4b6da5913eea07d21a00b6a843265' 
  AND token = 'kji0Gfq8aBzvTzWjUhTTvaVacFKhBs823QlZm0CXNa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}