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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37ddadc4972e8c571b1e9f139762191d802849ef5d23c5da39f76d144f958c9b' 
  AND token = 'LrgT6jx/kNslLdZxRfua423JtXdcLb10MhNra2CXk4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}