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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01a04f942653c2f1c833d1f59fe0f64ee9f00697745b38ab46e287bcab446632' 
  AND token = 'fuG6yytehn0GEYtAmf7puZVA3/BF3E3wQxmZeMm18io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}