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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f486bc0aa828ac4911f463ab1ab3d742c44c2799cc36fcae9098a419a4559c86' 
  AND token = 'HoGyjRI8YNOeyjSznqpwGf00ngfiftrbxgWc4uhqGV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}