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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7289ffb206b07a7a4da869e6dcace484ef1014af70f35f5a1dc3fbf93a03ec2' 
  AND token = 'qAfDM7YQSlRI50BfuSOTNzEaj/GTq6UhcRvtm1y6sAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}