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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ef899c06b807979ffe41e7e0ab44945d506fd975a8dac002c4e028a293a6ab7' 
  AND token = 'Jks58po4y/b1u1vNdp8+aI1mq8vIbWwOA0y3gOBiEdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}