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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc8995cc1b99ff8b23167519c52f8d16068bc9f654b1efb7783c34193ac619ed' 
  AND token = 'lU3JPOPnVmUw7cyQG+itx+QGRFMjf8x/aUu5n/sSxD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}