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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d2266ab60896baf70d92e07ba6468117c10cd59e480608483f3d30bc3ecf9d9' 
  AND token = 'BygRa+EtM/1lh8n8TGK7HdkS56qyI1wmdTOcPPFWVbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00231

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}