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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51e1c4869d8d82f2b4f3971555c8d84951caf6b048e6d3bdaa729d5bcbec5de2' 
  AND token = 'v1pe9M1HZQFRIbayVric/o24yFBBkC/fC7+2Z7TQwPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}