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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72843c3b4e952f93d799d15e55d641ee32b66eab16a0eb9aa574513c2a21e643' 
  AND token = 't332xVPpPlVFy0BiutJpHzy/e9Q4xeQz/EoxpPGyo9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}