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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51602b038b2f4951d0b0f9726cdfbde68a76a20458173103c9e1b8b6e77dddd1' 
  AND token = '9QcIcoOPimBJVsAdxf3rcKbjSMqTrFCJp3Vcv62BXYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}