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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1990619676e81be7dbf78ab0b5cec2cf5e4f52e8d69f1f78c495221bfc48a4f3' 
  AND token = 'HAqFwVtj1bxSiep4maK0iS2blM1XlETPwjVoHwBOGwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}