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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a733ecd1b63b8c30d6841b59a49994a80dfe4f32449d6d453e444b0a0e95dcb' 
  AND token = '/UXsXGaHk7g2l8e8WjIoPZTbIaitTGHpH2m9G3rwidI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}