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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a26d157d0e5b750b2374ac7c166919f8a4a913bd988546c2407aa31dd157fb59' 
  AND token = 'TQrk2tkO3ea6rifqeMSvmspdogHgAI4VLFqxUcbQZxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}