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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80da94b873e00028a2e53c921837a42cf160f8ba46115005ae2293821a0775cd' 
  AND token = 'lCMXPBEBXagtui9aMXsbjd/oG6JrrckkzowYdbDbOfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}