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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '209399247b74f504ef096e6a943499d1443324fdb5e2b75f963caf5bdd26d8d3' 
  AND token = '+RorAiSqjjICLNLOaqkttsriudSmlZBk//62KOoRj8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}