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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27b486878b4b114e58d14ace9526b06235166350d85d6c47003202e35e14efd5' 
  AND token = 'C3j/ljtaj1rr/LI35mk6vzxGzRXtcz+mxy2srPUHxpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}