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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2eccd04f7656c89f8242f2be2f93c56f1e11bdc5cd64551c3f1cf01a0003135' 
  AND token = 'V9r9z0FO5OjVqLpRRu2gqmCuDPfBgRVIznR8y5NE20Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}