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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e3f8e8b5785f1c66a2584a8f0dfe38058feea59bdbe2ec9ac2330de526111eb' 
  AND token = 'BEBTum6FIUl8oWLq50exg5EjVYkmSVhMLfux+NayDgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}