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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5db5fb7d5095c64075fa5fb865e773c3714f88966871bce9fb1f85fb9c847b09' 
  AND token = 'oykQQHjFQX1umk3Eh0sN/mE6OsrQyuT8bWwKUwK8yZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}