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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ab56daba780926ad449b01fcfa51f42034233e00dc7b8f39fcb5a7978a7a21' 
  AND token = 'VI8baPGwzI/c1UVFQMeVyMnifAQ8Ulgk/C4NBP2KzfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}