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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486dc7cac73e04961b92fbbadf166ccfc8dd0286fe673ae83a03af6190363b54' 
  AND token = 'S5L49d+ZlPSgl1CQhos/VUQsO5ibP8KEBcg1vtXA78k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}